Anti-VAChT Antibody FL490 Conjugate (N425/45)

Name: Anti-VAChT Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-429-FL490
Price: 486.0 USD
Availability: InStock

Our mouse VAChT FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N425/45. It detects mouse and rat VAChT and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-VAChT Antibody FL490 Conjugate

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Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-429-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

VAChT

Scientific Background

Vesicular acetylcholine transporter (VaCht), or Solute Carrier Family 18 Member A3 is encoded by the gene Slc18a3 and is a member of the vesicular amine transporter family. VaCht transports acetylcholine into secretory vesicles for release into the extracellular space. VaCht is expressed in major cholinergic cell groups in the peripheral and central cholinergic nervous systems. Diseases associated with SLC18A3 include Myasthenic Syndrome and Presynaptic and Presynaptic Congenital Myasthenic Syndromes.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N425/45

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Slc18a3 Vacht Vat

Molecular Weight

60 kDa

Immunogen

Fusion protein amino acids 55-125 (first vesicle lumen domain) of rat VAChT (accession number Q62666) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940424

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with VMAT1 or VMAT2

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Vesicular acetylcholine transporter (VAChT) (rVAT) (Solute carrier family 18 member 3)

UniProt ID

Q62666

Shipping

Shipped on ice packs

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Anti-VAChT Antibody FL490 Conjugate (N425/45)

SKU: 75-429-FL490

Product Details

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