Anti-VAChT Antibody (N425/45)

Name: Anti-VAChT Antibody
Brand: NeuroMab
SKU: 75-429
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N425/45

Applications

ICC, IHC

Host Species

Mouse

Format

Purified

Gene Name

Slc18a3 Vacht Vat

Molecular Weight

60 kDa

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Adult rat trigeminal and facial motor nuclei immunohistochemistry.

Volume: 100 µL

Variant

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Product Details

Target

Vesicular acetylcholine transporter (VAChT) (rVAT) (Solute carrier family 18 member 3)

Target Description

Vesicular acetylcholine transporter (VaCht), or Solute Carrier Family 18 Member A3 is encoded by the gene Slc18a3 and is a member of the vesicular amine transporter family. VaCht transports acetylcholine into secretory vesicles for release into the extracellular space. VaCht is expressed in major cholinergic cell groups in the peripheral and central cholinergic nervous systems. Diseases associated with SLC18A3 include Myasthenic Syndrome and Presynaptic and Presynaptic Congenital Myasthenic Syndromes.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N425/45

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Slc18a3 Vacht Vat

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 55-125 (first vesicle lumen domain) of rat VAChT (also known as Vesicular acetylcholine transporter, Solute carrier family 18 member 3, Vat and Slc18a3, accession number Q62666); Mouse: 97% identity (69/71 amino acids identical); Human: 84% identity (60/71 amino acids identical); 40% identity with VMAT1 and other vesicular transporters

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2632411

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with VMAT1 or VMAT2

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Vesicular acetylcholine transporter (VAChT) (rVAT) (Solute carrier family 18 member 3)

UniProt Details

UniProt (Human): Q16572
UniProt (Immunogen Species): Q62666

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Anti-VAChT Antibody (N425/45)

Anti-VAChT Antibody
SKU: 75-429

Bulk Order Anti-VAChT Antibody

Product Details

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Anti-VAChT Antibody (N425/45)

Anti-VAChT Antibody SKU: 75-429

Bulk Order Anti-VAChT Antibody

Product Details

Anti-VAChT Antibody
SKU: 75-429