Anti-TRIP8B (Exon 1A/5 Junction) Antibody FL550 Conjugate (N291C/22)

Name: Anti-TRIP8B (Exon 1A/5 Junction) Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-334-FL550
Price: 486.0 USD
Availability: InStock

Our mouse TRIP8b (exon 1a/5 junction) FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N291C/22. It detects mouse and rat TRIP8b (exon 1a/5 junction) and is purified by Protein A chromatography. Works in ICC.

Anti-TRIP8B (Exon 1A/5 Junction) Antibody FL550 Conjugate

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Species Reactivity

Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-334-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

TRIP8b (exon 1a/5 junction)

Scientific Background

PEX5-related protein, Peroxisomal Biogenesis Factor 5 Like, TPR-containing Rab8b-interacting protein or TRIP8b is encoded by the gene Pex5l. It is a member of the peroxisomal targeting signal receptor family. TRIP8b is a cytoplasmic accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. TRIP8b interacts with the carboxyl-terminal region of HCN channels and regulates their cell-surface expression to the dendrites in many types of neurons. TRIP8b plays a role in regulation of HCN channel cyclic nucleotide kinetics. TRIP8b is expressed in the brain. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N291C/22

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Pex5l Pex2 Pex5r Pxr2

Molecular Weight

60 kDa

Immunogen

Synthetic peptide amino acids 1-12 (MYQGHMQLVNEQ, exon 1a (yellow) and exon 5 (green) of constant region) of mouse TRIP8b (accession number Q8C437)

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940153

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Specific for exon 1a/5 junction (does not react

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

PEX5-related protein (PEX2-related protein) (PEX5-like protein) (Peroxin-5-related protein) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b)

UniProt ID

Q8C437

Shipping

Shipped on ice packs

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Anti-TRIP8B (Exon 1A/5 Junction) Antibody FL550 Conjugate (N291C/22)

SKU: 75-334-FL550

Product Details

Bulk Order Anti-TRIP8B (Exon 1A/5 Junction) Antibody FL550 Conjugate

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