Anti-TRAAK Potassium Channel Antibody FL650 Conjugate (N445/27)

Name: Anti-TRAAK Potassium Channel Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-433-FL650
Price: 486.0 USD
Availability: InStock

Our mouse TRAAK potassium channel FL650 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N445/27. It detects mouse and rat TRAAK potassium channel and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-TRAAK Potassium Channel Antibody FL650 Conjugate

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Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Biotin

Carrier-Free

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Data Sheet

SKU: 75-433-FL650

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

TRAAK potassium channel

Scientific Background

Potassium two pore domain channel subfamily K member 4 is encoded by the gene KCNK4. KCNK4 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK4 homodimerizes and functions as an outwardly rectifying channel. KCNK4 is regulated by polyunsaturated fatty acids, temperature, and mechanical deformation of the lipid membrane. KCNK4 is expressed in the brain, spinal cord, and eye. Diseases associated with KCNK4 include Facial Dysmorphism, Hypertrichosis, Epilepsy, Intellectual/Developmental Delay, and Gingival Overgrowth Syndrome.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N445/27

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnk4 Traak

Molecular Weight

43 kDa

Immunogen

Fusion protein amino acids 256-398 (cytoplasmic C-terminus) of mouse TRAAK (accession number O88454) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940443

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with TREK1/KCNK2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK)

UniProt ID

O88454

Shipping

Shipped on ice packs

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Anti-TRAAK Potassium Channel Antibody FL650 Conjugate (N445/27)

SKU: 75-433-FL650

Product Details

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