Anti-TRAAK Potassium Channel Antibody (N445/27)

Name: Anti-TRAAK Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-433
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N445/27

Applications

ICC, IHC

Host Species

Mouse

Format

Purified

Gene Name

Kcnk4 Traak

Molecular Weight

43 kDa

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Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-TRAAK Potassium Channel Antibody

Product Details

Target

Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK)

Target Description

Potassium two pore domain channel subfamily K member 4 is encoded by the gene KCNK4. KCNK4 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK4 homodimerizes and functions as an outwardly rectifying channel. KCNK4 is regulated by polyunsaturated fatty acids, temperature, and mechanical deformation of the lipid membrane. KCNK4 is expressed in the brain, spinal cord, and eye. Diseases associated with KCNK4 include Facial Dysmorphism, Hypertrichosis, Epilepsy, Intellectual/Developmental Delay, and Gingival Overgrowth Syndrome.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N445/27

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnk4 Traak

Molecular Weight

43 kDa

Antigen

Fusion protein amino acids 256-398 (cytoplasmic C-terminus) of mouse TRAAK (also known as Potassium channel subfamily K member 4, TWIK-related arachidonic acid-stimulated potassium channel protein, Two pore potassium channel KT4.1 and Kcnk4, accession number O88454); Rat: 97% identity (139/143 amino acids identical); Human: 81% identity (116/143 amino acids identical); 50% identity with TREK1/KCNK2 and other KCNK channels

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2629424

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with TREK1/KCNK2

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK)

UniProt Details

UniProt (Human): Q9NYG8
UniProt (Immunogen Species): O88454

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Anti-TRAAK Potassium Channel Antibody (N445/27)

Anti-TRAAK Potassium Channel Antibody
SKU: 75-433

Bulk Order Anti-TRAAK Potassium Channel Antibody

Product Details

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Anti-TRAAK Potassium Channel Antibody (N445/27)

Anti-TRAAK Potassium Channel Antibody SKU: 75-433

Bulk Order Anti-TRAAK Potassium Channel Antibody

Product Details

Anti-TRAAK Potassium Channel Antibody
SKU: 75-433