Anti-TRAAK Potassium Channel Antibody (N445/27)

Name: Anti-TRAAK Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-433
Price: 319.0 USD
Availability: InStock

Our Anti-TRAAK potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N445/27. It detects mouse and rat TRAAK potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-433

Volume: 100 µL

Variant

Price:

$319

Quantity:

Product Details

Target

TRAAK potassium channel

Target Description

Potassium two pore domain channel subfamily K member 4 is encoded by the gene KCNK4. KCNK4 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK4 homodimerizes and functions as an outwardly rectifying channel. KCNK4 is regulated by polyunsaturated fatty acids, temperature, and mechanical deformation of the lipid membrane. KCNK4 is expressed in the brain, spinal cord, and eye. Diseases associated with KCNK4 include Facial Dysmorphism, Hypertrichosis, Epilepsy, Intellectual/Developmental Delay, and Gingival Overgrowth Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N445/27

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnk4 Traak

Molecular Weight

43 kDa

Antigen

Fusion protein amino acids 256-398 (cytoplasmic C-terminus) of mouse TRAAK (accession number O88454) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2629424

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with TREK1/KCNK2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK)

UniProt Details

UniProt (Human): Q9NYG8
UniProt (Immunogen Species): O88454

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Anti-TRAAK Potassium Channel Antibody (N445/27)

SKU: 75-433

Product Details

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