Anti-Slc18a2/VMAT2 Antibody FL490 Conjugate (N449/73)

Name: Anti-Slc18a2/VMAT2 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-436-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Slc18a2/VMAT2 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N449/73. It detects human, mouse, and rat Slc18a2/VMAT2 and is purified by Protein A chromatography. Works in ICC.

Anti-Slc18a2/VMAT2 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-436-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Slc18a2/VMAT2

Scientific Background

Vesicular neurotransmitter transporters sequester the transmitters into synaptic vesicles (Erickson et al., 1996). The vesicular monoamine transporter 2 (VMAT2) is responsible for catecholamine and serotonin storage in central synapses. Antibodies specific for VMAT have been used to monitor expression of the transporter during development and in aging and can be effectively used as a marker for monoamine terminals (Haycock et al., 2003; Witkovsky et al., 2005).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N449/73

Isotype

IgG2b

Applications

ICC

Host Species

Mouse

Gene Name

Slc18a2

Molecular Weight

60 kDa

Immunogen

Fusion protein amino acids 42-132 (first lumenal domain) of mouse Slc18a2 (accession number Q66L40) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940452

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Slc18a1/VMAT1 or Slc18a3/VAChT

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Slc18a2 protein

UniProt ID

Q66L40

Shipping

Shipped on ice packs

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Anti-Slc18a2/VMAT2 Antibody FL490 Conjugate (N449/73)

SKU: 75-436-FL490

Product Details

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