Anti-Slc18a2/VMAT2 Antibody FL650 Conjugate (N449/73)

Name: Anti-Slc18a2/VMAT2 Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-436-FL650
Price: 460.0 USD
Availability: InStock

Our Anti-Slc18a2/VMAT2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N449/73. It detects human, mouse, and rat Slc18a2/VMAT2, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

594

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Data Sheet

SKU: 75-436-FL650

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Slc18a2/VMAT2

Target Description

Vesicular neurotransmitter transporters sequester the transmitters into synaptic vesicles (Erickson et al., 1996). The vesicular monoamine transporter 2 (VMAT2) is responsible for catecholamine and serotonin storage in central synapses. Antibodies specific for VMAT have been used to monitor expression of the transporter during development and in aging and can be effectively used as a marker for monoamine terminals (Haycock et al., 2003; Witkovsky et al., 2005).

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N449/73

Isotype

IgG2b

Applications

ICC

Host Species

Mouse

Gene Name

Slc18a2

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 42-132 (first lumenal domain) of mouse Slc18a2 (accession number Q66L40) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940455

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with Slc18a1/VMAT1 or Slc18a3/VAChT

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Slc18a2 protein

UniProt Details

UniProt (Human): Q05940
UniProt (Immunogen Species): Q66L40

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Anti-Slc18a2/VMAT2 Antibody FL650 Conjugate (N449/73)

SKU: 75-436-FL650

Product Details

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