Anti-Kv8.2 Potassium Channel Antibody FL490 Conjugate (N448/88)

Name: Anti-Kv8.2 Potassium Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-435-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Kv8.2 potassium channel FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N448/88. It detects mouse Kv8.2 potassium channel and is purified by Protein A chromatography. Works in ICC.

Anti-Kv8.2 Potassium Channel Antibody FL490 Conjugate

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Species Reactivity

Mouse

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-435-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kv8.2 potassium channel

Scientific Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. Members of the Kv5-Kv11 families code for “silent subunits” that do not express as functional homomultimers. In heterologous expression systems, silent subunits can coassemble with Kv2 and Kv3 subunits and modulate the biophysical characteristics of the latter subunits (Yan L. et al., 2004).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N448/88

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnv2

Molecular Weight

65 kDa

Immunogen

Fusion protein amino acids 1-163 (cytoplasmic N-terminus) of mouse Kv8.2 (accession number Q8CFS6) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse

Antibody Registry ID

AB_2940448

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2)

UniProt ID

Q8CFS6

Shipping

Shipped on ice packs

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Anti-Kv8.2 Potassium Channel Antibody FL490 Conjugate (N448/88)

SKU: 75-435-FL490

Product Details

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