Anti-Kv8.2 Potassium Channel Antibody (N448/88)

Name: Anti-Kv8.2 Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-435
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

ICC, WB

Host Species

Mouse

Gene Name

Kcnv2

Molecular Weight

65 kDa

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$Immunoblot against membrane fractions from adult rat brain (RBM) and heart (RHM) and Kcnv2-S2 mouse wild-type (+/+) and higher-expressing transgenic (Tg/+) brains probed with N448/88 (left) and N52A/42 (right) TC supe. Mouse brain samples courtesy of Jennifer Kearney (Northwestern).$

Immunoblot against membrane fractions from adult rat brain (RBM) and heart (RHM) and Kcnv2-S2 mouse wild-type (+/+) and higher-expressing transgenic (Tg/+) brains probed with N448/88 (left) and N52A/42 (right) TC supe. Mouse brain samples courtesy of Jennifer Kearney (Northwestern).

Product Details

Target

Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2)

Target Description

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. Members of the Kv5-Kv11 families code for “silent subunits” that do not express as functional homomultimers. In heterologous expression systems, silent subunits can coassemble with Kv2 and Kv3 subunits and modulate the biophysical characteristics of the latter subunits (Yan L. et al., 2004).

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N448/88

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

Kcnv2

Molecular Weight

65 kDa

Antigen

Fusion protein amino acids 1-163 (cytoplasmic N-terminus) of mouse Kv8.2 (also known as Potassium voltage-gated channel subfamily V member 2, Kcnv2 and rCG_63626, accession number Q8CFS6); Rat: 85% identity (138/163 amino acids identical); Human: 70% identity (115/164 amino acids identical)

Species Reactivity

Mouse

Antibody Registry ID

AB_2651161

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2)

UniProt Details

UniProt (Human): Q8TDN2
UniProt (Immunogen Species): Q8CFS6

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Anti-Kv8.2 Potassium Channel Antibody (N448/88)

Anti-Kv8.2 Potassium Channel Antibody
SKU: 75-435

Product Details

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Anti-Kv8.2 Potassium Channel Antibody (N448/88)

Anti-Kv8.2 Potassium Channel Antibody SKU: 75-435

Product Details

Anti-Kv8.2 Potassium Channel Antibody
SKU: 75-435