Our mouse Kv1.4 potassium channel (extracellular) FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone L71/5. It detects mouse and rat Kv1.4 potassium channel (extracellular) and is purified by Protein A chromatography. Works in ICC.
Potassium voltage-gated channel subfamily A member 4 or Kv1.4 is encoded by the gene KCNA4. Kv1.4 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.4 is expressed in brain, and at lower levels in the testis, lung, kidney, colon, heart and adrenal tissue. In brain, Kv1.4 is located in the soma, dendrite and axon terminus of neurones in most regions of the brain.
Purified by Protein A chromatography
Lot dependent: provided at 0.3-0.5 mg/mL
Monoclonal
L71/5
IgG1
ICC
Mouse
Kcna4
98 kDa
Fusion protein amino acids 336-370 (DDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFN, extracellular S1-S2 linker) of rat Kv1.4 (accession number P15385) produced recombinantly in E. Coli
Rat
Mouse, Rat
AB_2940104
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Potassium voltage-gated channel subfamily A member 4 (RCK4) (RHK1) (RK3) (Voltage-gated potassium channel subunit Kv1.4)
