Tissue and transfected cell immunoblot: extracts of crude adult rat brain membrane (RBM) and COS cells transiently transfected with untagged Kv1.4 or Kv2.1 plasmid and probed with L71/5 (left), K13/31 (middle) or K89/34 (right) TC supe.
Bulk Order Anti-Kv1.4 Potassium Channel (Extracellular) Antibody
Potassium voltage-gated channel subfamily A member 4 (RCK4) (RHK1) (RK3) (Voltage-gated potassium channel subunit Kv1.4)
Potassium voltage-gated channel subfamily A member 4 or Kv1.4 is encoded by the gene KCNA4. Kv1.4 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.4 is expressed in brain, and at lower levels in the testis, lung, kidney, colon, heart and adrenal tissue. In brain, Kv1.4 is located in the soma, dendrite and axon terminus of neurones in most regions of the brain.
Fusion protein amino acids 336-370 (DDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFN, extracellular S1-S2 linker) of rat Kv1.4 (also known as Potassium voltage-gated channel subfamily A member 4, HPCN2, Voltage-gated K(+) channel HuKII or HBK4 or HK1, Kcna4, KCNA4L, RCK4, RHK1 and RK3, accession number P15385) Mouse: 100% identity (35/35 amino acids identical) Human: 91% identity (32/35 amino acids identical) Less than 50% identity with other Kv1 potassium channel subunits
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.