Anti-KA2 Kainate Receptor Antibody FL490 Conjugate (N279B/27)

Name: Anti-KA2 Kainate Receptor Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-362-FL490
Price: 486.0 USD
Availability: InStock

Our mouse KA2 kainate receptor FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N279B/27. It detects mouse and rat KA2 kainate receptor and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-KA2 Kainate Receptor Antibody FL490 Conjugate

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Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-362-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

KA2 kainate receptor

Scientific Background

Glutamate Ionotropic Receptor Kainate Type Subunit 5 is encoded by the gene GRIK5. GRIK5 is a member of the glutamate-gated ion channel (TC 1.A.10.1) family, GRIK5 subfamily. GRIK5 forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. GRIK5 is highly expressed in the cerebral cortex, pyriform cortex, caudate-putamen, hippocampal complex, medial habenulata, and granule cell layer of the cerebellum. GRIK5 is weakly expressed in the globus pallidus, thalamus, colliculi, and the reticular thalamic nucleus. Diseases associated with GRIK5 include Schizophrenia and Autosomal Recessive Non-Syndromic Intellectual Disability.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N279B/27

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Grik5

Molecular Weight

110 kDa

Immunogen

Fusion protein amino acids 825-979 (cytoplasmic C-terminus) of rat KA2 kainate receptor (accession number Q63273) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940212

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with KA1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Glutamate receptor ionotropic, kainate 5 (GluK5) (Glutamate receptor KA-2) (KA2)

UniProt ID

Q63273

Shipping

Shipped on ice packs

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Anti-KA2 Kainate Receptor Antibody FL490 Conjugate (N279B/27)

SKU: 75-362-FL490

Product Details

Bulk Order Anti-KA2 Kainate Receptor Antibody FL490 Conjugate

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