Anti-Cavbeta1 Ca2+ Channel Antibody (BSA and Azide free) (N7/18)

Name: Anti-Cavbeta1 Ca2+ Channel Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-052-CF
Price: 486.0 USD
Availability: InStock

Our mouse Cavbeta1 Ca2+ channel carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N7/18. It detects human, mouse, non-human primate, and rat Cavbeta1 Ca2+ channel and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Anti-Cavbeta1 Ca2+ Channel Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

SKU: 75-052-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Cavbeta1 Ca2+ channel

Scientific Background

Voltage-dependent L-type calcium channel subunit beta-1 or Cav ß1 is encoded by the gene CACNB1. Cavß1 is a cytoplasmic subunit of L type voltage-sensitive calcium channels. These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cavß1 serves to regulate the activity of L-type calcium channels. Cavß1 expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Diseases associated with CACNB1 include Malignant Hyperthermia and epileptic encephalopathy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N7/18

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

CACNB1 CACNLB1

Molecular Weight

80, 55 kDa

Immunogen

Synthetic peptide amino acids 19-34 of human Cav1 (PMEVFDPSPQGKYSKR; accession number NP_059042)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not cross-react with Cavβ2, Cavβ3, Cavβ4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1)

UniProt ID

Q02641

Shipping

Shipped on ice packs

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Anti-Cavbeta1 Ca2+ Channel Antibody (BSA and Azide free) (N7/18)

SKU: 75-052-CF

Product Details

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