Anti-Cavbeta1 Ca2+ Channel Antibody (N7/18)
Primary Antibody
Human, Mouse, Rat
N7/18
IHC, IP, WB
Mouse
Purified
CACNB1 CACNLB1
80, 55 kDa
![Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N7/18 (left) or N52A/42 (right) TC supe.](http://cdn.shopify.com/s/files/1/0014/8806/0475/products/validation-image-73-052-n7-18-wb-1_{width}x.jpg?v=1626905493)
Adult rat hippocampus immunohistochemistry.
![Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N7/18 (left) or N52A/42 (right) TC supe.](http://cdn.shopify.com/s/files/1/0014/8806/0475/products/validation-image-73-052-n7-18-wb-1_1024x.jpg?v=1626905493)
Product Specific References for Applications and Species
- Immunocytochemistry: Human | Mouse
- Immunohistochemistry: Mouse | Rat
- Immunoprecipitation: Mouse | Rat
- Western Blot: Human | Mouse | Non-Human Primate | Rat
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 30071129 | 1:2000 | Campiglio, M., et al. 2018. STAC3 incorporation into skeletal muscle triads occurs independent of the dihydropyridine receptor. Journal of Cellular Physiology, 9045-9051. |
| 28112192 | 1:2000 | Campiglio, M. , et al. 2017. STAC3 stably interacts through its C1 domain with CaV1.1 in skeletal muscle triads. Scientific Reports, 41003. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36161458 | 1:2000 | Tuinte, W.E., et al. 2022. STAC3 Determines the Slow Activation Kinetics of CaV 1.1 Currents and Inhibits its Voltage-Dependent Inactivation. Journal of Cellular Physiology, . |
| 32616470 | 1:50 | Held, R.G., et al. 2020. Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ channels and Ca2+ Entry. Neuron, 667-683. |
| 25384984 | not listed | Eltit, J.M., et al. 2014. Amino acid residues 489-503 of dihydropyridine receptor (DHPR) β1a subunit are critical for structural communication between the skeletal muscle DHPR complex and type 1 ryanodine receptor.. The Journal of Biological Chemistry, 36116-36124. |
| 19996312 | 1:10,000 | Obermair, G.J., et al. 2010. Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.. Journal of Biological Chemistry, 5776-5791. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 29949772 | 1:1000 | Kaplan, M.M., et al. 2018. Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation. Cell Reports, 3891-3904. |
| 22737983 | 1:250 | Ferrándiz-Huertas, C., et al. 2012. Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.. Journal of Neurochemistry, 1095-1107. |
| 21228161 | not listed | Chen, J., et al. 2011. Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.. Journal of Neuroscience, 512-525. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 21804529 | 1:100 | Favereaux, A., et al. 2011. Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain. EMBO Journal, 3830-3841. |
| 20509142 | 5ug/ml | Ortiz-Miranda, S.I., et al. 2010. Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals.. Journal of Cellular Physiology, 276-288. |
| 19755859 | 1:2000 | Subramanyam, P., et al. 2009. Activity and calcium regulate nuclear targeting of the calcium channel beta4b subunit in nerve and muscle cells.. Channels, 343-355. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 19840220 | 10ug | Abiria, S.A., et al. 2010. CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation.. Journal of Neurochemistry, 150-161. |
| Immunoprecipitation: Rat | ||
| PMID | Dilution | Publication |
| 19840220 | 10ug | Abiria, S.A., et al. 2010. CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation.. Journal of Neurochemistry, 150-161. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 31403402 | 1:500 | Morgenstern, T.J., et al. 2019. A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits. Elife, e49253. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 30760886 | 1:1000 | Jin, J., et al. 2020. Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Molecular Psychiatry, 1035-1049. |
| 29212769 | not listed | Perez, C.F., et al. 2018. Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-β1a subunit (CACNB1). American Journal of Physiology, C323-C333. |
| 22737983 | 1:1000 | Ferrándiz-Huertas, C., et al. 2012. Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.. Journal of Neurochemistry, 1095-1107. |
| 19840220 | not listed | Abiria, S.A., et al. 2010. CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation.. Journal of Neurochemistry, 150-161. |
| Western Blot: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 18535142 | not listed | Ravindran, A., et al. 2008. Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits.. PNAS: USA, 8154-8159. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 24751537 | not listed | Béguin, P., et al. 2014. BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis.. The Journal of Biology, 233-249. |
| 19840220 | not listed | Abiria, S.A., et al. 2010. CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation.. Journal of Neurochemistry, 150-161. |