Anti-Beta1-Spectrin Antibody FL490 Conjugate (N385/21)

Name: Anti-Beta1-Spectrin Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-374-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Beta1-spectrin FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N385/21. It detects human, mouse, and rat Beta1-spectrin and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Beta1-Spectrin Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-374-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Beta1-spectrin

Scientific Background

Spectrin beta chain, erythrocytic, Beta1 spectrin, or Membrane Cytoskeletal Protein is encoded by the gene SPTB and is a member of the member of the spectrin gene family. Beta1 spectrin is primary member of the cytoskeletal network in the erythrocyte plasma membrane. Beta1 spectrin is involved in cell membrane organization and stability and associates with the proteins band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Diseases associated with this gene include Spherocytosis and Elliptocytosis.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N385/21

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

SPTB SPTB1

Molecular Weight

250 kDa

Immunogen

Fusion protein amino acids 1555-2137 (C-terminal repeats 13 to 17) of human Beta1-spectrin (accession number P11277) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940248

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Spectrin beta chain, erythrocytic (Beta-I spectrin)

UniProt ID

P11277

Shipping

Shipped on ice packs

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Anti-Beta1-Spectrin Antibody FL490 Conjugate (N385/21)

SKU: 75-374-FL490

Product Details

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