Anti-ANO6/TMEM16F Antibody FL550 Conjugate (N429/19)

Name: Anti-ANO6/TMEM16F Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-418-FL550
Price: 486.0 USD
Availability: InStock

Our mouse ANO6/TMEM16F FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N429/19. It detects human, mouse, and rat ANO6/TMEM16F and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-ANO6/TMEM16F Antibody FL550 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-418-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

ANO6/TMEM16F

Scientific Background

Anoctamin-6, Transmembrane Protein 16F or -ANO6/TMEM16F is encoded by the gene ANO6. ANO6 belongs to the anoctamin family of membrane proteins many of which are calcium-activated chloride channels. ANO6 plays a role as a regulator of phospholipid scrambling in platelets (which is involved in blood clotting). ANO6 is expressed in epithelial tissues. Diseases associated with ANO6 include Scott Syndrome and Miyoshi Muscular Dystrophy 3.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N429/19

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ANO6 TMEM16F

Molecular Weight

110 kDa

Immunogen

Fusion protein amino acids 1-294 (cytoplasmic N-terminus) of human ANO6 (accession number Q4KMQ2) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940389

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not cross-react with ANO5/TMEM16E

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)

UniProt ID

Q4KMQ2

Shipping

Shipped on ice packs

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Anti-ANO6/TMEM16F Antibody FL550 Conjugate (N429/19)

SKU: 75-418-FL550

Product Details

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