Anti-Slo2.2/Slack K+ Channel Antibody FL650 Conjugate (N3/26)

Name: Anti-Slo2.2/Slack K+ Channel Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-051-FL650
Price: 543.0 USD
Availability: InStock

Our mouse Slo2.2/Slack K+ channel FL650 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N3/26. It detects human, marine mollusk, mouse, and rat Slo2.2/Slack K+ channel and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-Slo2.2/Slack K+ Channel Antibody FL650 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-051-FL650

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Slo2.2/Slack K+ channel

Scientific Background

Potassium channel subfamily T member 1 or -KCNT1/Slo2.2/Slack K+ channel is encoded by the gene KCNT1. Slo2.2 is a member of the the voltage-gated ion channel (vic) superfamily, and the KCNT protein family, which is made of KCNT1 and KCNT2. Slo2.2 functions as an outwardly rectifying potassium channel subunit to contribute to ion conductance and signaling pathways. Slo2.2 can be activated by high intracellular sodium or chloride levels. Slo2.2 is expressed at the membrane in many areas of the brain, brainstem, spinal cord, spleen and liver. Mutations in this gene cause the early-onset epileptic disorders

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N3/26

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnt1 Slack

Molecular Weight

140 kDa

Immunogen

Fusion protein amino acids 1168-1237 of rat Slo2.2 (accession number NP_068625) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939227

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)

UniProt ID

Q9Z258

Shipping

Shipped on ice packs

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Anti-Slo2.2/Slack K+ Channel Antibody FL650 Conjugate (N3/26)

SKU: 75-051-FL650

Product Details

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