Anti-Melanocyte-stimulating hormone, gamma (Gamma-MSH) Antibody

Name: Anti-Melanocyte-stimulating hormone, gamma (Gamma-MSH) Antibody
Brand: Biosensis
SKU: GP-031-50
Price: 327.0 USD
Availability: InStock

Our Anti-Melanocyte-stimulating hormone, gamma (Gamma-MSH) guinea pig polyclonal primary antibody detects human and sheep Melanocyte-stimulating hormone, gamma (Gamma-MSH), and is whole serum. It is validated for use in IHC-Frozen.

The cryostat section of the sheep hypothalamus was incubated in guinea pig polyclonal antibodies to the gamma melanocyte-stimulating hormone at the dilution of 1:1000 overnight followed by incubation with FITC- conjugated secondary antibodies. Cell bodies and nerve terminals in the sheep brain are intensely stained.

Anti-Melanocyte-stimulating hormone, gamma (Gamma-MSH) Antibody

The cryostat section of the sheep hypothalamus was incubated in guinea pig polyclonal antibodies to the gamma melanocyte-stimulating hormone at the dilution of 1:1000 overnight followed by incubation with FITC- conjugated secondary antibodies. Cell bodies and nerve terminals in the sheep brain are intensely stained.

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Species Reactivity

Human, Sheep

Applications

IHC

Host Species

Guinea Pig

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Data Sheet

SKU: GP-031-50

Volume/Size: 50 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Melanocyte-stimulating hormone, gamma (Gamma-MSH)

Scientific Background

Proopiomelanocortin (POMC) is the precursor of the melanocortin peptides alpha, beta and gamma. POMC neurons in the arcuate nucleus of the hypothalamus function as key central regulators of food intake and homeostatic control of energy balance in both rodents and non-human primates.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

IHC

Host Species

Guinea Pig

Immunogen

A synthetic peptide (YVMGHFRWDRFG) corresponding to the amino acids 77-88 from human Proopiomelanocortin (POMC). POMC is the precursor of the melanocortin peptides alpha, beta and gamma. The synthetic peptide was conjugated to carrier protein to enhance the immunological response.

Immunogen Species

Human

Species Reactivity

Human, Sheep

Storage

Spin vial briefly before opening. Reconstitute in 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C or lower. After reconstitution, divide into aliquots and store at -20°C, or lower, for optimal long term stability. It is recommended that a reconstituted aliquot is stored at 2-8°C for no longer than 2 weeks. Allocation of an appropriate anti-bacterial agent can increase shelf life by several weeks. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this.

Physical State

Lyophilized

Production Notes

Whole serum

Dilution Ranges

IHC: 1:2000

Application Details

This antibody shows excellent staining on sheep and human tissue. Rodent tissues demonstrate high background staining.

Conjugate

Unconjugated

Specificity

Human. Specificity was demonstrated by immunohistochemistry. This antiserum is known to react with sheep gamma MSH. Other species have not yet been tested.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (lyophilized, unopened vial).

Synonyms

Gamma-melanocyte stimulating hormone; Melanotropin gamma; Corticotropin-lipotropin [Precursor]; Pro-opiomelanocortin; POMC

UniProt ID

P01189

Shipping

25°C (ambient)

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Anti-Melanocyte-stimulating hormone, gamma (Gamma-MSH) Antibody

SKU: GP-031-50

Product Details

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