Anti-Vitronectin Antibody (A18)

Name: Anti-Vitronectin Antibody
Brand: Antibodies Incorporated
SKU: CSI 004-18-010
Price: 425.0 USD
Availability: InStock

Our mouse Vitronectin monoclonal antibody from Antibodies Incorporated is produced in-house from clone A18. It detects bovine, horse, and rabbit Vitronectin and is Protein A or Protein G purified. Works in ELISA, IHC, AP.

Anti-Vitronectin Antibody

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Species Reactivity

Bovine, Horse

Applications

ELISA, IHC

Host Species

Mouse

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Data Sheet

SKU: CSI 004-18-010

Volume: 100 uL

Variant

Price:

$425.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Vitronectin

Scientific Background

Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

A18

Isotype

IgG1/k

Applications

ELISA, IHC

Host Species

Mouse

Gene Name

VTN

Molecular Weight

65 kDa, 75 kDA

Immunogen

Lysed bovine corneal endothelial cells and extracellular matrix

Immunogen Species

Bovine

Species Reactivity

Bovine, Horse

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Application Details

CSI 004-18 reacts weakly in ELISA with vitronectin coated directly onto the microtiter plate. CSI 004-18 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues. The antibody can be used as an affinity purification reagent of vitronectin from bovine plasma or serum and to quantitatively deplete plasma or serum of vitronectin. It can also be used to probe vitronectin conformation.

Conjugate

Unconjugated

Specificity

CSI 004-18 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). The antibody inhibits integrin-mediated cell adhesion to bovine vitronectin. It can be used to probe vitronectin conformation.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B

UniProt ID

Q3ZBS7

NCBI Gene ID

507525

Shipping

Shipped on ice packs

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Anti-Vitronectin Antibody (A18)

SKU: CSI 004-18-010

Product Details

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