Anti-Thrombospondin 1 Antibody (A65M)

Name: Anti-Thrombospondin 1 Antibody
Brand: Antibodies Incorporated
SKU: CSI 002-65-010
Price: 450.0 USD
Availability: InStock

Our mouse Thrombospondin 1 monoclonal antibody from Antibodies Incorporated is produced in-house from clone A65M. It detects bovine and human Thrombospondin 1 and is Protein A or Protein G purified. Works in ELISA, IHC, IP.

Anti-Thrombospondin 1 Antibody

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Species Reactivity

Bovine, Human

Applications

ELISA, IHC

Host Species

Mouse

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Data Sheet

SKU: CSI 002-65-010

Volume: 100 uL

Variant

Price:

$450.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Thrombospondin 1

Scientific Background

Thrombospondin 1 (TSP1) is a multidomain, multifunctional glycoprotein from platelets and certain vascular cells which has been shown to play an important role in cell-cell and cell-matrix interactions. TSP1 is a calcium-sensitive, disulfide-bonded trimer with a subunit molecular mass of 150 kDa. TSP1 exists in different conformational states depending on the calcium ion concentration used in the purification buffers. (1)

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

A65M

Isotype

IgG1/k

Applications

ELISA, IHC

Host Species

Mouse

Gene Name

THBS1

Molecular Weight

129 kDA, appears at 150 kDa on WB due to glycosylation

Immunogen

Extracellular matrix material from cultured bovine corneal endothelial cells

Immunogen Species

Bovine

Species Reactivity

Bovine, Human

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Application Details

CSI 002-65 can be used in ELISA. (1) CSI 002-65 for immunostaining of frozen periodate-lysine-paraformaldehyde-fixed sections of bovine and human tissues. CSI 002-65 can also be used to probe for the low-calcium conformation of thrombospondin. (1)

Conjugate

Unconjugated

Specificity

CSI 002-65 is highly specific for the low-calcium (0.1 mmol/L) conformation of human TSP1. There is no evidence of cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin). Epitope is only present in thrombospondin prepared in low-calcium (0.1 mmol/L) buffers.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

THBS1, THBS, THBS-1, TSP, TSP-1, TSP1, thrombospondin-1, glycoprotein G, thrombospondin-1p180, thrombospondin-p50

UniProt ID

P07996

NCBI Gene ID

7057

Shipping

Shipped on ice packs

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Anti-Thrombospondin 1 Antibody (A65M)

SKU: CSI 002-65-010

Product Details

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