Anti-Factor XII (heavy chain) Antibody (13799)

Name: Anti-Factor XII (heavy chain) Antibody
Brand: Antibodies Incorporated
SKU: CAM 011-37-010
Price: 450.0 USD
Availability: InStock

Our mouse Factor XII (heavy chain) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 13799. It detects human Factor XII (heavy chain) and is Protein A or Protein G purified. Works in ELISA, WB.

Anti-Factor XII (heavy chain) Antibody

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Species Reactivity

Human

Applications

ELISA, WB

Host Species

Mouse

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Data Sheet

SKU: CAM 011-37-010

Volume: 100 uL

Variant

Price:

$450.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Factor XII (heavy chain)

Scientific Background

Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

13799

Isotype

IgG2a/k

Applications

ELISA, WB

Host Species

Mouse

Gene Name

F12

Molecular Weight

50 kDa

Immunogen

Affinity purified human factor XII.

Immunogen Species

Human

Species Reactivity

Human

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Application Details

CAM 011-37 was used in ELISA. CAM 011-37 as a capture antibody (1.6 μg/mL) was used in combination with biotinylated CAM 011-05 (1μg/mL) to measure total factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. (1) CAM 011-37 was used in western blot to detect factor XII, α-factor XIIa C1-inh complexes and α-factor XIIa. (1)

Conjugate

Unconjugated

Specificity

CAM 011-37 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. Differs from CAM 011-05.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

F12, HAE3, HAEX, HAF, coagulation factor XII, Hageman factor, Plasma coagulation Factor XIIa, beta-factor XIIa part 1, beta-factor XIIa part 2, coagulation factor XIIa heavy chain, coagulation factor XIIa light chain

UniProt ID

P00748

NCBI Gene ID

2161

Shipping

Shipped on ice packs

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Anti-Factor XII (heavy chain) Antibody (13799)

SKU: CAM 011-37-010

Product Details

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