Our mouse D-Dimer monoclonal antibody from Antibodies Incorporated is produced in-house from clone 22. It detects canine and human D-Dimer and is Protein A or Protein G purified. Works in ELISA, WB.
D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.
Protein A or Protein G purified
1 mg/mL ±15%
Monoclonal
22
IgG1/k
ELISA, WB
Mouse
FGA, FGB, FGG
180 kDa
Purified human D-dimer
Human
Canine, Human
2-8°C without exposure to light
Liquid
BSA free
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
ABS 015-22 binds free D-dimer in solution. ABS 015-022 works as a capture antibody in sandwich ELISA with biotinylated ABS 015-22 or ABS 015-28 as a detection antibody. Biotinylated ABS 015-22 works as a detection antibody in sandwich ELISA for D-dimer with itself (ABS 015-22) or ABS 015-28 as a capture antibody. The combination with ABS 015-28 as a capture antibody and ABS 015-22B as a detection antibody is recommended. Due to reducing conditions in Western blotting ABS 015-22 binds the alpha-chain (12kDa) of D-Dimer, and not the entire D-Dimer complex.
Unconjugated
ABS 015-22 binds human D-dimer. Cross-reacts < 2% with directly coated D-monomer but not with directly coated fibrinogen. When tested in a pair with itself, with ABS 015-28 and with a fibrinogen-specific polyclonal antibody, the epitope appears to relate to the dimerization site of D-dimer.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
FGA, AMYLD2, Fib2, fibrinogen alpha chain, fibrinogen, A alpha polypeptide, FGB, HEL-S-78p, fibrinogen beta chain, beta-fibrinogen, epididymis secretory sperm binding protein Li 78p, fibrinogen, B beta polypeptide, FGG, fibrinogen gamma chain, fibrinogen, gamma polypeptide, testicular tissue protein Li 70
