Anti-TARPGamma2/4/8 Antibody Biotin Conjugate (N245/36)

Name: Anti-TARPGamma2/4/8 Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-252-BTN
Price: 543.0 USD
Availability: InStock

Our mouse TARPGamma2/4/8 biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N245/36. It detects mouse and rat TARPGamma2/4/8 and is purified by Protein A chromatography. Works in ELISA, ICC, WB.

Anti-TARPGamma2/4/8 Antibody Biotin Conjugate

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-252-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

TARPGamma2/4/8

Scientific Background

Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N245/36

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Cacng2 Stg Cacng4 Cacng8

Molecular Weight

36 kDa

Immunogen

Fusion Protein Amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (accession number Q71RJ2) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

Cross-react with TARPGamma4 and TARPGamma8Does not cross-react with TARPGamma3

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

AW060990 antibody; Voltage-dependent calcium channel gamma-2 subunit; B230105C07Rik antibody; Neuronal voltage-gated calcium channel gamma-2 subunit; B930041E13Rik antibody; Stargazin; Cacng2 antibody; Transmembrane AMPAR regulatory protein gamma-2; Calcium channel voltage dependent gamma subunit 2 antibody; TARP gamma-2 Voltage-dependent calcium channel gamma-4 subunit; CaV gamma 2 antibody; Neuronal voltage-gated calcium channel gamma-4 subunit; CCG2_HUMAN antibody; Transmembrane AMPAR regulatory protein gamma-4; Ipr328 antibody; TARP gamma-4 Voltage-dependent calcium channel gamma-8 subunit; MGC123981 antibody; Neuronal voltage-gated calcium channel gamma-8 subunit; MGC138502 antibody; Transmembrane AMPAR regulatory protein gamma-8; MGC138504 antibody; TARP gamma-8; Neuronal voltage gated calcium channel gamma 2 subunit antibody; Neuronal voltage-gated calcium channel gamma-2 subunit antibody; Stargazer antibody; stg antibody; TARP gamma-2 antibody; Transmembrane AMPAR regulatory protein gamma-2 antibody; Voltage dependent calcium channel gamma 2 subunit antibody; Voltage-dependent calcium channel gamma-2 subunit antibody; Wag antibody; Waggler antibody

UniProt ID

Q71RJ2
UniProt Summary: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

NCBI Gene ID

84347

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Anti-TARPGamma2/4/8 Antibody Biotin Conjugate (N245/36)

SKU: 75-252-BTN

Product Details

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