Anti-CNGA1 and CNGA3 Antibody (L36/12)

Name: Anti-CNGA1 and CNGA3 Antibody
Brand: NeuroMab
SKU: 75-107
Price: 337.0 USD
Availability: InStock

Our mouse CNGA1 and CNGA3 monoclonal antibody from NeuroMab is produced in-house from clone L36/12. It detects human, mouse, rat, and zebrafish CNGA1 and CNGA3 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Crude lysate of 7-day old zebrafish larvae immunoblot.

Isolated goldfish cone immunohistochemistry. Data courtesy of Diane Henry-Vanisko and Gary Matthews.

Zebrafish retina immunohistochemistry. Data courtesy of Diane Henry-Vanisko and Gary Matthews.

Rat retina immunohistochemistry. Data courtesy of Diane Henry-Vanisko and Gary Matthews.

Crude lysate of 7-day old zebrafish larvae immunoblot.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat, Zebrafish

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-107

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

CNGA1 and CNGA3

Scientific Background

This antibody recognizes both Cyclic Nucleotide Gated Channel Subunit Alpha 1 and Cyclic Nucleotide Gated Channel Subunit Alpha 3, which are both members of the cyclic nucleotide-gated cation channel family. These ion channels function in response to the binding of cyclic nucleotides. CNG channels are nonselective cation channels that are found in the membranes of various tissue and cell types, and are significant in sensory transduction as well as cellular development.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L36/12

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Cnga3 Cng3

Molecular Weight

80 kDa (size will vary depending on species and isoform)

Immunogen

Fusion protein amino acids 535-637 (cytoplasmic C-terminus) of goldfish CNG (accession number AAO16601) produced recombinantly in E. Coli

Immunogen Species

Goldfish

Species Reactivity

Human, Mouse, Rat, Zebrafish

Antibody Registry ID

AB_10672375

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.35

Dilution Ranges

IHC: 1:1000

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Doc2-beta; Cyclic nucleotide-gated cation channel alpha-3; Cone photoreceptor cGMP-gated channel subunit alpha; Cyclic nucleotide-gated channel alpha-3; CNG channel alpha-3; CNG-3; CNG3

UniProt ID

AAO16601
UniProt Summary: May promote neurite outgrowth of developing thalamic neurons.

NCBI Gene ID

1259/1261

Shipping

Shipped on ice packs

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Anti-CNGA1 and CNGA3 Antibody (L36/12)

SKU: 75-107

Product Details

Bulk Order Anti-CNGA1 and CNGA3 Antibody

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