Anti-RGS14 Recombinant Chicken Chimeric mAb FL550 Conjugate (N133/21)

Name: Anti-RGS14 Recombinant Chicken Chimeric mAb FL550 Conjugate
Brand: Aves Labs
SKU: 78-170-FL550
Price: 562.0 USD
Availability: InStock

Our chicken Anti-RGS14 FL550 conjugate recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N133/21. It detects mouse and rat RGS14 and is purified by affinity chromatography. KO validated. Works in IHC, ICC.

Anti-RGS14 Recombinant Chicken Chimeric mAb FL550 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 78-170-FL550

Volume: 200 µL

Variant

Price:

$562.00

Quantity:

Ships: 1-5 business days

Product Details

Target

RGS14

Scientific Background

RGS14 is a member of the RGS family (regulator of G-protein signaling) and is highly expressed in the prefrontal cortex. Hallmark domains of RGS14 include a RGS domain, two Raf-like Ras-binding domains and a GoLoco motif. RGS14 inactivates G protein α subunits. Alterations in this protein have been implicated in Schizophrenia and Alzheimer’s disease.

Format

Purified by affinity chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Recombinant

Clone

N133/21

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

Rgs14

Molecular Weight

60 kDa

Excitation / Emission

FL550 Ex: 550 nm, Em: 575 nm

Immunogen

Fusion protein amino acids 1-544 (full-length) of rat RGS14 (accession number O08773) produced recombinantly in E. Coli

Immunogen Species

Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N133/21 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N133/21 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Conjugate

550

Specificity

Does not react with RGS12

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Regulator of G-protein signaling 14 (RGS14)

UniProt ID

O08773

Shipping

Shipped on ice packs

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Anti-RGS14 Recombinant Chicken Chimeric mAb FL550 Conjugate (N133/21)

SKU: 78-170-FL550

Product Details

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