Anti-Rem2 Antibody (N324/2)

Name: Anti-Rem2 Antibody
Brand: NeuroMab
SKU: 75-286
Price: 337.0 USD
Availability: InStock

Our mouse Rem2 monoclonal antibody from NeuroMab is produced in-house from clone N324/2. It detects mouse and rat Rem2 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Transfected cell immunoblot: extracts of COS cells transiently transfected with HA-tagged Rem2, Rem, Flag-tagged Rad or untagged Gem or Kv2.1 plasmid and probed with N324/2 (left) or 12CA5 (right) TC supe.

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Click on image to zoom

Species Reactivity

Mouse, Zebrafish

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-286

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Rem2

Scientific Background

Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007). REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N324/2

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Rem2

Molecular Weight

45 kDa (and larger due to oligomerization)

Immunogen

Fusion protein amino acids 1-341 (full-length) of rat Rem2 (accession number Q9WTY2)

Immunogen Species

Rat

Species Reactivity

Mouse, Zebrafish

Antibody Registry ID

AB_11001585

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Rad, Gem or Rem1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)

UniProt ID

Q9WTY2

Shipping

Shipped on ice packs

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Anti-Rem2 Antibody (N324/2)

SKU: 75-286

Product Details

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