Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody FL490 Conjugate (N4/49)

Name: Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-061-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Pink1 PTEN induced putative kinase 1 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N4/49. It detects human, mouse, and rat Pink1 PTEN induced putative kinase 1 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-061-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Pink1 PTEN induced putative kinase 1

Scientific Background

PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N4/49

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

PINK1

Molecular Weight

63 kDa

Immunogen

Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939260

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

UniProt ID

Q9BXM7

Shipping

Shipped on ice packs

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Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody FL490 Conjugate (N4/49)

SKU: 75-061-FL490

Product Details

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