Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody (N4/49)

Name: Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody
Brand: NeuroMab
SKU: 75-061
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human

Clone

N4/49

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

PINK1

Molecular Weight

63 kDa

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Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment.

Adult rat brain low-speed pellet immunoblot.

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody

Product Details

Target

Pink1 PTEN induced putative kinase 1

Target Description

PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N4/49

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

PINK1

Molecular Weight

63 kDa

Antigen

Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

Species Reactivity

Human

Antibody Registry ID

AB_2268255

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

UniProt Details

UniProt (Human): Q9BXM7
UniProt (Immunogen Species): Q9BXM7

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Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody (N4/49)

Available Conjugates

Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody
SKU: 75-061

Bulk Order Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody

Product Details

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Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody (N4/49)

Available Conjugates

Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody SKU: 75-061

Bulk Order Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody

Product Details

Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody
SKU: 75-061