Anti-NrCAM Antibody (N343/26)

Name: Anti-NrCAM Antibody
Brand: NeuroMab
SKU: 75-325
Price: 337.0 USD
Availability: InStock

Our mouse NrCAM monoclonal antibody from NeuroMab is produced in-house from clone N343/26. It detects mouse and rat NrCAM and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Immunofluorescence staining of a node of Ranvier in adult rat sciatic nerve with N343/26 (green) and bIV-spectrin rabbit polyclonal (red). Image courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine.

Click on image to zoom

Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-325

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

NrCAM

Scientific Background

Neuronal Cell Adhesion Molecule is encoded by the gene NRCAM. NRCAM is a member of the immunoglobulin superfamily, L1/neurofascin/NgCAM family. NRCAM is an ankyrin-binding protein that is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM also may play a role in cell-cell communication via signalling from its intracellular domain to the actin cytoskeleton during directional cell migration. NRCAM is expressed in the brain. Diseases associated with NRCAM include Masa Syndrome and Autism.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N343/26

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Nrcam Kiaa0343

Molecular Weight

160 kDa

Immunogen

Fusion protein amino acids 30-845 (extracellular domain) of mouse NrCAM (accession number Q810U4) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315900

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (mBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)

UniProt ID

Q810U4

Shipping

Shipped on ice packs

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Anti-NrCAM Antibody (N343/26)

SKU: 75-325

Product Details

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