Anti-Nav1.8 Na+ Channel Antibody (BSA and Azide free) (N134/12)

Name: Anti-Nav1.8 Na+ Channel Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-166-CF
Price: 486.0 USD
Availability: InStock

Our mouse Nav1.8 Na+ channel carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N134/12. It detects human, mouse, and rat Nav1.8 Na+ channel and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Anti-Nav1.8 Na+ Channel Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-166-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Nav1.8 Na+ channel

Scientific Background

NAV1.8 is a member of the voltage-gated sodium channel family, which function in producing and propagating action potentials. Sodium channels are composed of a large alpha subunit that may be associated with one or more smaller beta subunits. Nav 1.8 is an integral membrane glycoprotein that is responsible for the initial rising phase of action in most excitable cells. Nav 1.8 is expressed in neurons in the dorsal root ganglion (DRG). and appears to have a role in pain pathways.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N134/12

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Scn10a Sns

Molecular Weight

220 kDa

Immunogen

Fusion protein amino acids 1724-1956 (cytoplasmic C-terminus) of rat Nav1.8 (accession number Q62968) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not react with Nav1.7

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (Sensory neuron sodium channel) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)

UniProt ID

Q62968

Shipping

Shipped on ice packs

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Anti-Nav1.8 Na+ Channel Antibody (BSA and Azide free) (N134/12)

SKU: 75-166-CF

Product Details

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