Anti-Mitofusin-2 Antibody Biotin Conjugate (N153/5)

Name: Anti-Mitofusin-2 Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-173-BTN
Price: 543.0 USD
Availability: InStock

Our mouse Mitofusin-2 biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N153/5. It detects mouse and rat Mitofusin-2 and is purified by Protein A chromatography. KO validated. Works in ELISA, IHC, ICC, WB.

Anti-Mitofusin-2 Antibody Biotin Conjugate

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-173-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Mitofusin-2

Scientific Background

Mitofusin 2, or transmembrane GTPase Mfn2 (MFN2) is a mitochondrial membrane protein with GTPase activity that functions to aid mitochondrial clustering and fusion. It may also play a role in mitochondrial metabolism. It is expressed in the outer membrane of mitochondria. MFN2 is expressed in many tissues including the heart, skeletal muscle, tongue, and brain. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI,

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N153/5

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Mfn2 Kiaa0214 Marf

Molecular Weight

90 kDa

Immunogen

Fusion Protein Amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2 (accession number Q80U63) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity against Mitofusin-1

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Mitofusin-2 (EC 3.6.5.-) (Hypertension-related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein) (Transmembrane GTPase MFN2)

UniProt ID

Q80U63

Shipping

Shipped on ice packs

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Anti-Mitofusin-2 Antibody Biotin Conjugate (N153/5)

SKU: 75-173-BTN

Product Details

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