Anti-Malin Antibody FL490 Conjugate (N85/18)

Name: Anti-Malin Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-128-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Malin FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N85/18. It detects human, mouse, non-human primate, and rat Malin and is purified by Protein A chromatography. Works in ICC.

Anti-Malin Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-128-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Malin

Scientific Background

NHL Repeat Containing E3 Ubiquitin Protein Ligase 1 is encoded by the gene NHLRC1. NHLRC1 is an E3 ubiquitin-protein ligase which is involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. NHLRC1 is expressed in the brain, spinal cord, heart, liver, skeletal muscle, and pancreas. Diseases associated with NHLRC1 include Myoclonic Epilepsy of Lafora and Epilepsy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N85/18

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

NHLRC1 EPM2B

Molecular Weight

42 kDa

Immunogen

Fusion protein amino acids 2-125 (N-terminus encompassing RING domain) of human Malin (also known as NHL repeat-containing protein 1, E3 ubiquitin-protein ligase NHLRC1, NHLRC1 and EPM2B, accession number Q6VVB1)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Antibody Registry ID

AB_2939476

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1)

UniProt ID

Q6VVB1

Shipping

Shipped on ice packs

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Anti-Malin Antibody FL490 Conjugate (N85/18)

SKU: 75-128-FL490

Product Details

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