Immunoblot against extracts of COS cells transiently transfected with Flag-tagged Malin or untagged Kv2.1 plasmid probed with N85/18 TC supe (left) or rabbit polyclonal (right).
NHL Repeat Containing E3 Ubiquitin Protein Ligase 1 is encoded by the gene NHLRC1. NHLRC1 is an E3 ubiquitin-protein ligase which is involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. NHLRC1 is expressed in the brain, spinal cord, heart, liver, skeletal muscle, and pancreas. Diseases associated with NHLRC1 include Myoclonic Epilepsy of Lafora and Epilepsy.
Fusion protein amino acids 1-395 (full-length) of human malin (also known as NHL repeatcontaining protein 1 and EPM2B, accession number AAQ19671); Rat: 83% identity (330/393 amino acids identical); Mouse: 83% identity (319/380 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.