Anti-Kvbeta2 K+ Channel Antibody Biotin Conjugate (K17/70)

Name: Anti-Kvbeta2 K+ Channel Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-021-BTN
Price: 543.0 USD
Availability: InStock

Our mouse Kvbeta2 K+ channel biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone K17/70. It detects finch, human, mouse, non-human primate, rat, Xenopus, and zebrafish Kvbeta2 K+ channel and is purified by Protein A chromatography. KO validated. Works in ELISA, IHC, ICC, WB, IP.

Anti-Kvbeta2 K+ Channel Antibody Biotin Conjugate

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Species Reactivity

Finch, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-021-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kvbeta2 K+ channel

Scientific Background

Voltage-gated potassium channel subunit beta-2 or Kvß2 is encoded by the gene KCNAB2. Kvß2 is a member of the potassium channel, voltage-gated, shaker-related subfamily. Kvβ2 is a cytoplasmic subunit that modulates the characteristics of the membrane spanning, channel-forming alpha-subunits. Beta subunits can promote the closure of channels or enhance channel activity depending on other channel proteins. Kvβ2 is expressed in brain, in thecerebellum and in the juxtaparanodal region of nodes of Ranvier. Kvβ2 expression is also detected in lung, heart and kidney. Diseases associated with KCNAB2 include Chromosome 1P36 Deletion Syndrome and Juvenile Amyotrophic Lateral Sclerosis 16,

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

K17/70

Isotype

IgG1

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

Kcnab2 Ckbeta2 I2rf5 Kcnb3

Molecular Weight

38 kDa (major band), 41 kDa (minor band)

Immunogen

Fusion Protein Amino acids 1-367 (full length) of rat Kv2 (accession number NP_034728) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Finch, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (Neuroimmune protein F5)

UniProt ID

P62482

Shipping

Shipped on ice packs

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Anti-Kvbeta2 K+ Channel Antibody Biotin Conjugate (K17/70)

SKU: 75-021-BTN

Product Details

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