Anti-Kv7.2/KCNQ2 K+ channel Antibody (N26A/23)

Name: Anti-Kv7.2/KCNQ2 K+ channel Antibody
Brand: NeuroMab
SKU: 73-079
Price: 337.0 USD
Availability: InStock

Our mouse Kv7.2/KCNQ2 K+ channel monoclonal antibody from NeuroMab is produced in-house from clone N26A/23. It detects human, mouse, and rat Kv7.2/KCNQ2 K+ channel and is TC supernatant. Works in ELISA, IP, WB.

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS-1 cells transiently transfected with KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 or Kv2.1 plasmids and probed with pure N26A/23.

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, IP, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 73-079

Volume: 5 mL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Kv7.2/KCNQ2 K+ channel

Scientific Background

Potassium voltage-gated channel subfamily Q member 2 is encoded by the gene KCNQ2. KCNQ2 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.2/KCNQ2 sub-subfamily. KCNQ2 associates with KCNQ3 to form a potassium channel with nearly identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness of synaptic inputs. KCNQ2 is expressed in the brain and spinal cord. Diseases associated with KCNQ2 include Epileptic Encephalopathy, Early Infantile, 7 and Seizures, Benign Familial Neonatal 1.

Format

TC Supernatant

Concentration

Lot dependent

Clonality

Monoclonal

Clone

N26A/23

Isotype

IgG1

Applications

ELISA, IP, WB

Host Species

Mouse

Gene Name

KCNQ2

Molecular Weight

95 kDa

Immunogen

Fusion protein amino acids 1-59 (cytoplasmic N-terminus) of human KCNQ2 (also known as Potassium voltage-gated channel subfamily KQT member 2 or KvLQT2, Kv7.2 and KQT-like 2, accession number O43526); Rat: 96% identity (56/58 amino acids identical); Mouse: 96% identity (56/58 amino acids identical)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10673164

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Supernatant is harvested from hybridoma cells grown under standard cell culture conditions

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2)

UniProt ID

O43526

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Anti-Kv7.2/KCNQ2 K+ channel Antibody (N26A/23)

SKU: 73-079

Product Details

Bulk Order Anti-Kv7.2/KCNQ2 K+ channel Antibody

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