Anti-Kv6.4 Potassium Channel Antibody (BSA and Azide free) (N458/10)

Name: Anti-Kv6.4 Potassium Channel Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-458-CF
Price: 486.0 USD
Availability: InStock

Our mouse Kv6.4 potassium channel carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N458/10. It detects human, mouse, and rat Kv6.4 potassium channel and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Anti-Kv6.4 Potassium Channel Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

SKU: 75-458-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kv6.4 potassium channel

Scientific Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. Members of the Kv5-Kv11 families code for “silent subunits” that do not express as functional homomultimers. In heterologous expression systems, silent subunits can coassemble with Kv2 and Kv3 subunits and modulate the biophysical characteristics of the latter subunits (Yan L. et al., 2004).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N458/10

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Kcng4

Molecular Weight

60-80 kDa

Immunogen

Fusion protein amino acids 1-219 (cytoplasmic N-terminus) of mouse Kv6.4 (accession number Q80XM3) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4)

UniProt ID

Q80XM3

Shipping

Shipped on ice packs

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Anti-Kv6.4 Potassium Channel Antibody (BSA and Azide free) (N458/10)

SKU: 75-458-CF

Product Details

Bulk Order Anti-Kv6.4 Potassium Channel Antibody (BSA and Azide free)

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