Immunoblot against extracts of COS cells transiently transfected with Myc/Flag-tagged Kv6.1, Kv6.4 or untagged Kv2.1 plasmid probed with N458/10 (left) or rabbit anti-Flag (right)..
Anti-Kv6.4 Potassium Channel Antibody
Bulk Order Anti-Kv6.4 Potassium Channel Antibody
Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4)
Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. Members of the Kv5-Kv11 families code for “silent subunits” that do not express as functional homomultimers. In heterologous expression systems, silent subunits can coassemble with Kv2 and Kv3 subunits and modulate the biophysical characteristics of the latter subunits (Yan L. et al., 2004).
Fusion protein amino acids 1-219 (cytoplasmic N-terminus) of mouse Kv6.4 (also known as Voltage-gated potassium channel subunit Kv6.4, Potassium voltage-gated channel subfamily G member 4, Kcng4, KCNG3 and rCG_51585, accession number Q80XM3); Rat: 95% identity (207/219 amino acids identical); Human: 72% identity (161/225 amino acids identical); 50% identity with Kv6.1/KCNG1 and other potassium channel subunits
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.