Anti-Kv3.2 Potassium Channel Antibody Biotin Conjugate (N410/17)

Name: Anti-Kv3.2 Potassium Channel Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-397-BTN
Price: 543.0 USD
Availability: InStock

Our mouse Kv3.2 potassium channel biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N410/17. It detects human, mouse, and rat Kv3.2 potassium channel and is purified by Protein A chromatography. KO validated. Works in ELISA, IHC, ICC, WB.

Anti-Kv3.2 Potassium Channel Antibody Biotin Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-397-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kv3.2 potassium channel

Scientific Background

Potassium voltage-gated channel subfamily C member 2 or Kv3.2 potassium channel, is a member of the potassium channel, voltage-gated, shaker-related subfamily and the Shaw subfamily (the family includes 4 members Kv3.1-Kv3.4). Kv3.2 is primarily expressed in brain and found in the cortex and hippocampus. It has also been detected in the thalamus and caudate nucleus. Kv3.2 is a membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Diseases associated with KCNC2 include Spinocerebellar Ataxia 13 and Episodic Ataxia, Type 2

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N410/17

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnc2

Molecular Weight

80-100 kDa (varies due to post-translational modifications)

Immunogen

Fusion Protein Amino acids 474-613 (cytoplasmic C-terminus) of rat Kv3.2a (accession number P22462-3) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily C member 2 (Potassium channel voltage-gated Shaw-related subfamily C member 2) (Shaw-like potassium channel) (Voltage-gated potassium channel subunit Kv3.2)

UniProt ID

P22462-3

Shipping

Shipped on ice packs

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Anti-Kv3.2 Potassium Channel Antibody Biotin Conjugate (N410/17)

SKU: 75-397-BTN

Product Details

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