Anti-Kv11.3 Potassium Channel Antibody (N447/24)

Name: Anti-Kv11.3 Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-440
Price: 337.0 USD
Availability: InStock

Our mouse Kv11.3 potassium channel monoclonal antibody from NeuroMab is produced in-house from clone N447/24. It detects human, mouse, and rat Kv11.3 potassium channel and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Adult rat brain membrane immunoblot.

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-440

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Kv11.3 potassium channel

Scientific Background

ERG3 (ether-a-go-go–related gene 3), Potassium voltage-gated channel subfamily H member 7, or Kv11.3 potassium channel is encoded by the gene Kcnh7 and is a member of the ERG family of voltage activated potassium channels. Kv11.3 is a pore forming, alpha subunit of the potassium channel. Erg channels play roles in regulating the resting membrane potential and action potential duration. Kv11.3 is detected in total brain, in superior cervical, mesenteric and celiac ganglia, and at very low levels in retina and is also found in pituitary.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N447/24

Isotype

IgG2b

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnh7 Erg3

Molecular Weight

120 kDa

Immunogen

Fusion protein amino acids 894-1059 (cytoplasmic C-terminus) of rat Kv11.3 (accession number O54852) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2576199

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3)

UniProt ID

O54852

Shipping

Shipped on ice packs

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Anti-Kv11.3 Potassium Channel Antibody (N447/24)

SKU: 75-440

Product Details

Bulk Order Anti-Kv11.3 Potassium Channel Antibody

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