Anti-Kv1.1 K+ Channel (External) Antibody FL490 Conjugate (K36/15)

Name: Anti-Kv1.1 K+ Channel (External) Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-105-FL490
Price: 543.0 USD
Availability: InStock

Our mouse Kv1.1 K+ channel (external) FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone K36/15. It detects human, mouse, and rat Kv1.1 K+ channel (external) and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Kv1.1 K+ Channel (External) Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-105-FL490

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kv1.1 K+ channel (external)

Scientific Background

Potassium Channel Kv1.1or Kcna1 is a member of the Shaker potassium channel family. Kv1.1 is expressed in the brain, CNS and in the kidney. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.1 is involved with the regulation of cellular functions and the control of neuronal excitability. Mutations in Kv1.1 are associated with Episodic ataxia type 1 and epilepsy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

K36/15

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcna1

Molecular Weight

56 kDa (could be 65-85 kDa depending on glycosylation)

Immunogen

Synthetic peptide amino acids 191-208 (ELKDDKDFTGTIHRIDNTC, extracellular domain) of rat Kv1.1 (accession number P10499)

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939392

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1)

UniProt ID

P10499

Shipping

Shipped on ice packs

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Anti-Kv1.1 K+ Channel (External) Antibody FL490 Conjugate (K36/15)

SKU: 75-105-FL490

Product Details

Bulk Order Anti-Kv1.1 K+ Channel (External) Antibody FL490 Conjugate

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