Anti-Kv1.1 K+ Channel (External) Antibody (K36/15)

Name: Anti-Kv1.1 K+ Channel (External) Antibody
Brand: NeuroMab
SKU: 75-105
Price: 361.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

K36/15

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Kcna1

Molecular Weight

56 kDa (could be 65-85 kDa depending on glycosylation)

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Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)] probed with K36/15 (left) or N52A/42 (right) TC supe.

Immunoblot against crude brain membranes from adult rat (RBM) and Kv1.1 wild-type (WT) or knock-out (KO) mouse probed with K36/15 (left) or N52A/42 (right) TC supe.

Immunofluorescence staining of hippocampus from adult Kv1.1 wildtype (left) or knock-out (right) mouse with K36/15 (red) and K13/31 (green, Kv1.4).

Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)] probed with K36/15 (left) or N52A/42 (right) TC supe.

Volume: 100 µL

Variant

Price:

$361

Quantity:

Bulk Order Anti-Kv1.1 K+ Channel (External) Antibody

Product Details

Target

Kv1.1 K+ channel (external)

Target Description

Potassium Channel Kv1.1or Kcna1 is a member of the Shaker potassium channel family. Kv1.1 is expressed in the brain, CNS and in the kidney. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.1 is involved with the regulation of cellular functions and the control of neuronal excitability. Mutations in Kv1.1 are associated with Episodic ataxia type 1 and epilepsy.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K36/15

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcna1

Molecular Weight

56 kDa (could be 65-85 kDa depending on glycosylation)

Antigen

Synthetic peptide amino acids 191-208 (ELKDDKDFTGTIHRIDNTC, extracellular domain) of rat Kv1.1 (also known as potassium voltagegated channel subfamily A member 1, IA, RBKI, RCK1, accession number P10499); Mouse: 100% identity (18/18 amino acids identical); Human: 94% identity (17/18 amino acids identical)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2128566

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1)

UniProt Details

UniProt (Human): Q09470
UniProt (Immunogen Species): P10499

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Anti-Kv1.1 K+ Channel (External) Antibody (K36/15)

Anti-Kv1.1 K+ Channel (External) Antibody
SKU: 75-105

Bulk Order Anti-Kv1.1 K+ Channel (External) Antibody

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Anti-Kv1.1 K+ Channel (External) Antibody (K36/15)

Anti-Kv1.1 K+ Channel (External) Antibody SKU: 75-105

Bulk Order Anti-Kv1.1 K+ Channel (External) Antibody

Product Details

Anti-Kv1.1 K+ Channel (External) Antibody
SKU: 75-105