Anti-Kir6.2 Potassium Channel Antibody FL490 Conjugate (N363/71)

Name: Anti-Kir6.2 Potassium Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-393-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Kir6.2 potassium channel FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N363/71. It detects mouse and rat Kir6.2 potassium channel and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Kir6.2 Potassium Channel Antibody FL490 Conjugate

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Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-393-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kir6.2 potassium channel

Scientific Background

ATP-sensitive inward rectifier potassium channel 11 or Kir6.2 is encoded by the gene KCNJ11. Kir6.2 is an integral membrane protein which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Kir6.2 has broad expression in many tissues including brain, heart, pancreas (beta cells) and thyroid. Diseases associated with this gene include several forms of diabetes.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N363/71

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnj11

Molecular Weight

45 kDa

Immunogen

Fusion protein amino acids 345-390 (TARQLDEDRSLLDALTLASSRGPLRKRSVAVAKAKPKFSISPDSLS, cytoplasmic C-terminus) of rat Kir6.2 (accession number P70673) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940292

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Kir6.1

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

ATP-sensitive inward rectifier potassium channel 11 (BIR) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)

UniProt ID

P70673

Shipping

Shipped on ice packs

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Anti-Kir6.2 Potassium Channel Antibody FL490 Conjugate (N363/71)

SKU: 75-393-FL490

Product Details

Bulk Order Anti-Kir6.2 Potassium Channel Antibody FL490 Conjugate

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