Anti-Kir6.2 Potassium Channel Antibody (N363/71)

Name: Anti-Kir6.2 Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-393
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N363/71

Applications

ICC, IHC

Host Species

Mouse

Format

Purified

Gene Name

Kcnj11

Molecular Weight

45 kDa

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Immunoblot against extracts of COS cells transiently transfected with Myc-tagged Kir6.1, HA-tagged Kir6.2 or untagged Kv2.1 plasmid probed with N363/71 (left) or N52A/42 (right) TC supe.

Volume: 100 µL

Variant

Price:

$295

Quantity:

Bulk Order Anti-Kir6.2 Potassium Channel Antibody

Product Details

Target

ATP-sensitive inward rectifier potassium channel 11 (BIR) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)

Target Description

ATP-sensitive inward rectifier potassium channel 11 or Kir6.2 is encoded by the gene KCNJ11. Kir6.2 is an integral membrane protein which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Kir6.2 has broad expression in many tissues including brain, heart, pancreas (beta cells) and thyroid. Diseases associated with this gene include several forms of diabetes.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N363/71

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnj11

Molecular Weight

45 kDa

Antigen

Fusion protein amino acids 345-390 (TARQLDEDRSLLDALTLASSRGPLRKRSVAVAKAKPKFSISPDSLS, cytoplasmic C-terminus) of rat Kir6.2 (also known as ATP-sensitive inward rectifier potassium channel 11, Potassium channel inwardly rectifying subfamily J member 11, IKATP, Kcnj11 and BIR, accession number P70673); Mouse: 100% identity (46/46 amino acids identical); Human: 89% identity (41/46 amino acids identical); 50% identity with Kir6.1

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2491088

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Kir6.1

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

ATP-sensitive inward rectifier potassium channel 11 (BIR) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)

UniProt Details

UniProt (Human): Q14654
UniProt (Immunogen Species): P70673

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Anti-Kir6.2 Potassium Channel Antibody (N363/71)

Anti-Kir6.2 Potassium Channel Antibody
SKU: 75-393

Bulk Order Anti-Kir6.2 Potassium Channel Antibody

Product Details

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Anti-Kir6.2 Potassium Channel Antibody (N363/71)

Anti-Kir6.2 Potassium Channel Antibody SKU: 75-393

Bulk Order Anti-Kir6.2 Potassium Channel Antibody

Product Details

Anti-Kir6.2 Potassium Channel Antibody
SKU: 75-393