Anti-Kir3.3 Antibody FL550 Conjugate (N455/15)

Name: Anti-Kir3.3 Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-445-FL550
Price: 486.0 USD
Availability: InStock

Our mouse Kir3.3 FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N455/15. It detects human, mouse, and rat Kir3.3 and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-Kir3.3 Antibody FL550 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-445-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kir3.3

Scientific Background

Potassium inwardly rectifying channel subfamily J member 9 is encoded by the gene KCNJ9. KCNJ9 is a member of the inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ9 subfamily. KCNJ9 is an integral membrane protein and inward-rectifier type potassium channel, which has a greater tendency to allow potassium to flow into the cell rather than out of the cell. KCNJ9 is controlled by G-proteins and associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. KCNJ9 is expressed in the brain and skeletal muscle. Diseases associated with KCNJ9 include Pendred Syndrom and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, and Electrolyte Imbalance.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N455/15

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnj9 Girk3

Molecular Weight

40 kDa

Immunogen

Fusion protein amino acids 1-21 and 341-393 (fusion of cytoplasmic N- and C-termini) of mouse Kir3.3 (accession number P48543) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940481

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Inward rectifier K(+) channel Kir3.3 (Potassium channel, inwardlyrectifying subfamily J member 9) (G protein-activated inward rectifier potassium channel 3) (Kcnj9) (Girk3)

UniProt ID

P48543

Shipping

Shipped on ice packs

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Anti-Kir3.3 Antibody FL550 Conjugate (N455/15)

SKU: 75-445-FL550

Product Details

Bulk Order Anti-Kir3.3 Antibody FL550 Conjugate

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