Immunofluorescence staining of brain sections from adult Kir3.3 wild-type (WT) and knockout (KO) mouse cortex with N455/15 (Kir3.3, red) and K89/34 (Kv2.1, blue) TC supe. Tissue courtesy of Candice Contet (The Scripps Research Institute)..
Potassium inwardly rectifying channel subfamily J member 9 is encoded by the gene KCNJ9. KCNJ9 is a member of the inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ9 subfamily. KCNJ9 is an integral membrane protein and inward-rectifier type potassium channel, which has a greater tendency to allow potassium to flow into the cell rather than out of the cell. KCNJ9 is controlled by G-proteins and associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. KCNJ9 is expressed in the brain and skeletal muscle. Diseases associated with KCNJ9 include Pendred Syndrom and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, and Electrolyte Imbalance.
Fusion protein amino acids 1-21 and 341-393 (fusion of cytoplasmic N- and C-termini) of mouse Kir3.3 (also known as Inward rectifier K(+) channel Kir3.3, Potassium channel, inwardly rectifying subfamily J member 9, G protein-activated inward rectifier potassium channel 3, Kcnj9 and Girk3, accession number P48543)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.