Anti-Kir3.3 Antibody (N455/15)

Name: Anti-Kir3.3 Antibody
Brand: NeuroMab
SKU: 75-445
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N455/15

Applications

IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Kcnj9 Girk3

Molecular Weight

40 kDa

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Immunofluorescence staining of brain sections from adult Kir3.3 wild-type (WT) and knockout (KO) mouse cortex with N455/15 (Kir3.3, red) and K89/34 (Kv2.1, blue) TC supe. Tissue courtesy of Candice Contet (The Scripps Research Institute)..

Immunofluorescence staining of brain sections from adult Kir3.3 wild-type (WT) and knockout (KO) mouse cerebellum with N455/15 (Kir3.3, red) and K89/34 (Kv2.1, blue) TC supe. Tissue courtesy of Candice Contet (The Scripps Research Institute)..

Immunofluorescence staining of brain sections from adult Kir3.3 wild-type (WT) and knockout (KO) mouse cortex with N455/15 (Kir3.3, red) and K89/34 (Kv2.1, blue) TC supe. Tissue courtesy of Candice Contet (The Scripps Research Institute)..

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-Kir3.3 Antibody

Product Details

Target

Inward rectifier K(+) channel Kir3.3 (Potassium channel, inwardly rectifying subfamily J member 9) (G protein-activated inward rectifier potassium channel 3) (Kcnj9) (Girk3)

Target Description

Potassium inwardly rectifying channel subfamily J member 9 is encoded by the gene KCNJ9. KCNJ9 is a member of the inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ9 subfamily. KCNJ9 is an integral membrane protein and inward-rectifier type potassium channel, which has a greater tendency to allow potassium to flow into the cell rather than out of the cell. KCNJ9 is controlled by G-proteins and associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. KCNJ9 is expressed in the brain and skeletal muscle. Diseases associated with KCNJ9 include Pendred Syndrom and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, and Electrolyte Imbalance.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N455/15

Isotype

IgG2a

Applications

IHC, WB

Host Species

Mouse

Gene Name

Kcnj9 Girk3

Molecular Weight

40 kDa

Antigen

Fusion protein amino acids 1-21 and 341-393 (fusion of cytoplasmic N- and C-termini) of mouse Kir3.3 (also known as Inward rectifier K(+) channel Kir3.3, Potassium channel, inwardly rectifying subfamily J member 9, G protein-activated inward rectifier potassium channel 3, Kcnj9 and Girk3, accession number P48543)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2686912

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Inward rectifier K(+) channel Kir3.3 (Potassium channel, inwardlyrectifying subfamily J member 9) (G protein-activated inward rectifier potassium channel 3) (Kcnj9) (Girk3)

UniProt Details

UniProt (Human): Q92806
UniProt (Immunogen Species): P48543

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Anti-Kir3.3 Antibody (N455/15)

Anti-Kir3.3 Antibody
SKU: 75-445

Bulk Order Anti-Kir3.3 Antibody

Product Details

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Anti-Kir3.3 Antibody (N455/15)

Anti-Kir3.3 Antibody SKU: 75-445

Bulk Order Anti-Kir3.3 Antibody

Product Details

Anti-Kir3.3 Antibody
SKU: 75-445