Anti-JIP-2/IB-2 Antibody FL490 Conjugate (N135/37)

Name: Anti-JIP-2/IB-2 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-163-FL490
Price: 486.0 USD
Availability: InStock

Our mouse JIP-2/IB-2 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N135/37. It detects human, mouse, and rat JIP-2/IB-2 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-JIP-2/IB-2 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-163-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

JIP-2/IB-2

Scientific Background

Mitogen-activated protein kinase 8 interacting protein 2 is encoded by the gene MAPK8IP2. MAPK8IP2 is a member of the JIP scaffold family. MAPK8IP2 is a scaffold protein that is involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. MAPK8IP2 has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases. MAPK8IP2 is expressed in the brain and testis. Diseases associated with MAPK8IP2 include Cervical Verrucous Carcinoma and Isthmus Cancer.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N135/37

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Mapk8ip2 Ib2 Jip2

Molecular Weight

90 kDa

Immunogen

Fusion protein amino acids 226-421 of mouse JIP-2/IB-2 (accession number Q9ERE9) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939604

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not react with JIP-1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)

UniProt ID

Q9ERE9

Shipping

Shipped on ice packs

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Anti-JIP-2/IB-2 Antibody FL490 Conjugate (N135/37)

SKU: 75-163-FL490

Product Details

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