Anti-Iduna/RNF146 Antibody FL490 Conjugate (N201/35)

Name: Anti-Iduna/RNF146 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-233-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Iduna/RNF146 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N201/35. It detects human, mouse, and rat Iduna/RNF146 and is purified by Protein A chromatography. Works in ICC.

Anti-Iduna/RNF146 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-233-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Iduna/RNF146

Scientific Background

E3 ubiquitin-protein ligase RNF146, RING finger protein 146 or Iduna is encoded by the gene RNF146. Iduna is a ubiquitin protein ligase that is involved in ubiquitination and degradation. It is thought to be involved with diverse processes including DNA repair, activation of the Wnt signaling pathway, protection from DNA damage induced cell death. Iduna is found in many tissues including brain, heart, spleen, kidney and liver.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N201/35

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Rnf146

Molecular Weight

40 kDa

Immunogen

Fusion protein amino acids 1-359 (full-length) of mouse Iduna (accession number Q9CZW6) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939848

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

E3 ubiquitin-protein ligase RNF146 (EC 2.3.2.27) (Iduna) (RING finger protein 146) (RING-type E3 ubiquitin transferase RNF146)

UniProt ID

Q9CZW6

Shipping

Shipped on ice packs

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Anti-Iduna/RNF146 Antibody FL490 Conjugate (N201/35)

SKU: 75-233-FL490

Product Details

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