Anti-Iduna/RNF146 Antibody (N201/35)
Our Anti-Iduna/RNF146 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N201/35. It detects mouse and rat Iduna/RNF146, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Adult rat brain membrane immunoblot.
Product Specific References for Applications and Species
- Immunocytochemistry: Mouse
- Immunohistochemistry: Human | Mouse
- Immunoprecipitation: Mouse | Rat
- Western Blot: Human | Mouse | Rat
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 38272024 | 1:100 | Hou, S, et al. 2024. PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis. Molecular Cell, . |
| 28321181 | 1:50 | Yang, Y., et al. 2017. RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury. Frontiers in Cellular Neuroscience, 59. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 33443209 | 1:5000 | Kim, H., et al. 2020. Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death. Science Signaling, eaax7119. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 33443209 | 1:5000 | Kim, H., et al. 2020. Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death. Science Signaling, eaax7119. |
| 30974833 | 1:5000 | Kim, H., et al. 2019. Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. International Journal of Molecular Science, 1772. |
| 29290984 | 1:5000 | Kim, H., et al. 2017. Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models. Oncotarget, 106721-106739. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 38272024 | 1:100 | Hou, S, et al. 2024. PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis. Molecular Cell, . |
| Immunoprecipitation: Rat | ||
| PMID | Dilution | Publication |
| 28108258 | not listed | Yang, X., et al. 2017. Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia-ischemia. Neuroscience, 74-80. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 33443209 | 1:5000 | Kim, H., et al. 2020. Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death. Science Signaling, eaax7119. |
| 30974833 | 1:5000 | Kim, H., et al. 2019. Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. International Journal of Molecular Science, 1772. |
| 29290984 | 1:5000 | Kim, H., et al. 2017. Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models. Oncotarget, 106721-106739. |
| 28740101 | not listed | de Sousa, M.M.L., et al. 2017. p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage. Scientific Reports, 6322. |
| 23333241 | 1:1000 | Xu, H., et al. 2013. Iduna protects HT22 cells from hydrogen peroxide-induced oxidative stress through interfering poly(ADP-ribose) polymerase-1-induced cell death (parthanatos).. Cellular Signalling, 1018-1026. |
| 21825151 | not listed | Kang, H.C., et al. 2011. Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.. PNAS: USA, 14103-8. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 38272024 | 1:1000 | Hou, S., et al. 2024. PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis. Molecular Cell, . |
| 35544574 | not listed | Liu, L., et al. 2022. Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death. Science advances, eabh2332. |
| 33443209 | 1:5000 | Kim, H., et al. 2020. Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death. Science Signaling, eaax7119. |
| 31472117 | 1:1000 | Xu, H., et al. 2019. Iduna protects HT22 cells by inhibiting parthanatos: The role of the p53-MDM2 pathway. Experimental Cell Research, 111547. |
| 30974833 | 1:5000 | Kim, H., et al. 2019. Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. International Journal of Molecular Science, 1772. |
| 29290984 | 1:5000 | Kim, H., et al. 2017. Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models. Oncotarget, 106721-106739. |
| 28321181 | 1:1000 | Yang, Y., et al. 2017. RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury. Frontiers in Cellular Neuroscience, 59. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 28108258 | 1:1000 | Yang, X., et al. 2017. Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia-ischemia. Neuroscience, 74-80. |