Anti-Gs Protein, Alpha Subunit Antibody FL550 Conjugate (N192/12)

Name: Anti-Gs Protein, Alpha Subunit Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-211-FL550
Price: 486.0 USD
Availability: InStock

Our mouse Gs protein, alpha subunit FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N192/12. It detects human, mouse, and rat Gs protein, alpha subunit and is purified by Protein A chromatography. Works in ICC.

Anti-Gs Protein, Alpha Subunit Antibody FL550 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-211-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Gs protein, alpha subunit

Scientific Background

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short or Gs protein α subunit is encoded by the gene GNAS. Gsα is one of three subunits that make up a guanine nucleotide binding protein (Gprotein). The other proteins are a beta and a gamma subunit. G proteins are further divided into families depending on the type of α subunit included, G(S)alpha,G(Q)alpha,G(I)alpha,and G(12)alpha. Gsα functions as a transducer of numerous signaling pathways that are controlled by g protein coupled receptors (GPCRs) by coupling receptors to adenylyl cyclase and results in increased levels of the signaling molecule cAMP. Diseases associated with GNAS include Mccune-Albright Syndrome and Progressive Osseous Heteroplasia.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N192/12

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

GNAS GNAS1

Molecular Weight

45 kDa

Immunogen

Fusion protein amino acids 1-380 (full-length, short form) of bovine Gs protein alpha subunit (accession number P04896-2) produced recombinantly in E. Coli

Immunogen Species

Bovine

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939781

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Reacts with both Active and Inactive/QL forms

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)

UniProt ID

P04896-2

Shipping

Shipped on ice packs

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Anti-Gs Protein, Alpha Subunit Antibody FL550 Conjugate (N192/12)

SKU: 75-211-FL550

Product Details

Bulk Order Anti-Gs Protein, Alpha Subunit Antibody FL550 Conjugate

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