Anti-GluN3A/NR3A Antibody (N416/40)

Name: Anti-GluN3A/NR3A Antibody
Brand: NeuroMab
SKU: 75-416
Price: 337.0 USD
Availability: InStock

Our mouse GluN3A/NR3A monoclonal antibody from NeuroMab is produced in-house from clone N416/40. It detects mouse and rat GluN3A/NR3A and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Immunofluorescence staining of unpermerabilized COS cells transiently transfected with GFP- tagged GluN3A/NR3a and GluN1/NR1 plasmids with N416/40 (red). Images courtesy of Sonia Marco Martinez and Isabel Perez- Otano (University of Navarra).

Immunoblot against crude membranes from neonatal or adult rat brain (RBM) and extracts of COS cells transiently transfected with untagged GluN3A/NR3A or Kv2.1 plasmid probed with N416/40 (left) or K35/40 (right) TC supe.

Immunofluorescence staining of permeabilized.

Immunofluorescence staining of unpermerabilized COS cells transiently transfected with GFP- tagged GluN3A/NR3a and GluN1/NR1 plasmids with N416/40 (red). Images courtesy of Sonia Marco Martinez and Isabel Perez- Otano (University of Navarra).

Click on image to zoom

Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-416

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GluN3A/NR3A

Scientific Background

Glutamate receptor ionotropic, NMDA3A, N-Methyl-D-Aspartate Receptor Subtype 3A or GluN3A is encoded by the gene GRIN3A. GluN3A is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN3a is expressed in the CNS especially in development and appears to play a role in delaying synapse maturation. Diseases associated with GRIN3A include Macrodactyly

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N416/40

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Grin3a

Molecular Weight

110 kDa

Immunogen

Fusion protein amino acids 58-87 or 152-176 (extracellular N-terminus) of mouse GluN3A (accession number A2AIR5) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2532049

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Glutamate receptor ionotropic, NMDA3A

UniProt ID

A2AIR5

Shipping

Shipped on ice packs

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Anti-GluN3A/NR3A Antibody (N416/40)

SKU: 75-416

Product Details

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